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Soldiers guard Nepal’s parliament after two days of deadly protests

Armoured vehicles kept vigil in streets deserted except a few strollers, with shops and markets shut

NewsPakistan

India explores rare-earth deal with Myanmar rebels after Chinese curbs

India's foreign and mining ministries did not respond to Reuters' questions

NewsPakistan

Iranian border guards kill 6 Afghan migrants in Sistan-Baluchestan

HRANA condemns attack as a violation of fundamental rights

NewsPakistanWeather

Punjab launches Pakistan’s first airlift drone for flood rescues

Modern drone to aid Civil Defense in saving lives during natural disasters

EducationPakistan

Traveling photographer brings free art education to 150,000 rural children across Pakistan

Art is not a luxury but a basic need of the human mind and soul

Entertainment

David Bowie archive with 90,000 items to open to public in London

He died of cancer in 2016 aged 69, just two days after release of his final album, "Blackstar"

PakistanPolitics

PM declares propaganda against Pakistan Army intolerable

Premier pays tribute to Major Adnan during cabinet meeting

Crime and JusticePakistan

Rajab Butt responds after receiving NCCIA notice in gambling ads case

YouTuber says he expected the notice, vows legal response through his lawyers

PakistanTerroristsim

Govt forms peace committee to counter terrorism, extremism

Committee will operate under leadership of Atta Tarar

Crime and JusticePakistan

Bahrain and Pakistan decide to collaborate more on counterterrorism

Bahrain's interior minister meets Mohsin Naqvi

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Nick Reiner pleads not guilty in killing of parents Rob and Michele Reiner
Nick Reiner pleads not guilty in killing of parents Rob and Michele Reiner
Entertainment
The mystery of why some people develop ALS
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Health
What Ultra Processed foods do to gut microbiome health? Today, ultra-processed foods have become a part of our daily lives. These products, from packaged meals to ice-cream and bread in a package, stay fresh longer. However, research suggests that they could be harming the gut microbiome. In the human body, trillions of bacteria live. The gut microbiome is a system that supports digestion, immune function, metabolism and brain functions. It is often compared to a forest by experts. It becomes stronger and more stable the more it is diverse. Health problems can increase when gut bacteria become less diverse. Low microbial biodiversity is linked to inflammation, digestion problems, sleep disorders, and an increased risk of chronic diseases. A higher diversity is associated with improved health, and may even extend life. The addition of additives to ultra-processed foods raises concerns Foods that are ultra-processed often include emulsifiers and artificial sweeteners. They may also contain preservatives or food colours. These ingredients are added by manufacturers to enhance taste, texture and shelf-life. Emulsifiers help water and oil mix, for instance. These ingredients keep cakes, bread, and ice cream moist, even after weeks. They are found in thousands of products at supermarkets. Scientists are now questioning their effect over time on the gut bacteria, even though food safety agencies have approved them as safe for chemical and toxicity. Some additives, according to researchers, may disrupt the balance of bacteria in the gut. Studies show that emulsifiers can weaken mucus layers which separate bacteria and the intestinal wall. Researchers link Emulsifiers with Inflammation and Disease Early warning signals can be derived from animal studies. Researchers gave mice small quantities of emulsifiers in controlled experiments. These additives moved gut bacteria towards the intestinal wall. The change in the environment triggered an inflammation. Mice already prone to digestive disorders developed more severe symptoms. Mucus in the gut serves as a protective layer. Chronic inflammation may result when bacteria penetrate this mucus layer. Chronic inflammation can increase the risk for inflammatory bowel diseases and metabolic disorders.
What do ultra-processed foods do to gut microbiome health?
Health
Patients say that dopamine antagonist drugs are linked to gambling and other addictions. Patients in the UK report that medication prescribed to treat movement disorders led them into serious addictions such as gambling, sexual behavior, or compulsive buying. They claim that their doctors did not warn them of these dangers. Over 250 other people have told similar tales. These include police officers, nurses and doctors as well as a director of risk at a bank. The majority of them say that they did not have a history of addiction before beginning treatment. The Story of One Woman Who Lost PS30,000 Emma developed Restless Legs Syndrome during pregnancy. Ropinirole is a GSK dopamine-agonist that was prescribed by doctors. She began spending money and gambling excessively within months. The urges were uncontrollable, she says. She says, "It felt like I was being controlled by something." She lost more than PS30,000 in a single year. Her husband only found out about the link when he looked up her medications online. She claims that when she went to her GP with her gambling problem and medication usage, the doctor didn't make the connection. Emma asked later to alter her prescription. The financial damage was already done. She claims that it will take many years for her to pay off the debt. What are dopamine antagonists? These drugs are used to treat Parkinson's and Restless Legs Syndrome. These drugs stimulate dopamine production in the brain. Dopamine is a neurotransmitter that helps to control the movement of the body, as well as driving motivation and rewards. Some people become impulsive when dopamine levels increase too high. One in six Parkinson's sufferers who take these drugs have some sort of impulsive disorder. This side effect is very common. Many patients claim that the leaflets don't clearly describe how serious or specific this behavior can get. Some warning leaflets refer to impulse control issues in general but don't describe extreme gambling or pornography as addictions. Life, marriages and careers are affected Patients report devastating consequences. Patients report devastating consequences. Others began to invest recklessly. Some people began to make reckless investments. After starting this medication, several older women claim that their husbands began to be sexually aggressive. Families often did not know that the medication was responsible for the personality shifts. One reported incident involved a father who stole PS600,000.00 from his clients in order to pay for antiques and sex. Financial and emotional consequences led to a tragedy in the family. Increased pressure on regulators The prescription rate in England has not decreased, despite the fact that dopamine-agonists no longer represent a first-choice treatment for Restless Legs Syndrome. The UK Drug Regulator has been asked by lawmakers to examine whether the current warnings are too harsh. The patients want more clarity. Early information, say many, could have helped them save their relationships, finances and mental health.
Patients say that dopamine antagonist drugs are linked to gambling and other addictions.
Health
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